Relevant Publications:

Keung W, Chan PKW, Backeris PC, Lee EK, Wong N, Wong AOT, et al. Human Cardiac Ventricular-Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two-Tiered Assay for Inotropic Responses. Clinical Pharmacology and Therapeutics. 106(2):402-14.(2019)

Li, R. A., Keung, W., Cashman, T. J., Backeris, P. C., Chow, M. Z., Johnson, B. V., Bardot, E. S., Wong, A. O. T., Chan, P. K. W., Chan, C. W. Y., Costa K. D. Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells. Biomaterials. 163, 116-127 (2018).

Lee, E. J., Kim, D. E., Azeloglu, E. U. & Costa, K. D. Engineered cardiac organoid chambers: toward a functional biological model ventricle. Tissue Eng. Part A 14, 215–25 (2008).